Anti-CD68 Mouse mAb [56G56]

抗CD68小鼠单克隆抗体 [56G56]

Cat. No. A32016 Clone No. 56G56

SynonymsCD68, Macrosialin, Gp110, CD68

Host species Mouse
Reactivity Human, Mouse, Rat
Applications IHC, IF

详细信息 Product Information

Buffer
50% Glycerol, 0.5% BSA and 0.02% preservative in PBS (pH 7.2-7.4)
Purification
Antigen-affinity-purified
Concentration
Please check the information on the tube.
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Clonality
Monoclonal
Clone No.
56G56
Isotype
IgG2b, Kappa

抗原与靶点信息 Antigen & Target Information

Gene Name
CD68
Protein Name
CD68 molecule
Background
CD68 (Lysosomal-associated membrane glycoprotein CD68) belongs to mucin-like transmembrane glycoprotein family and executes lysosomal-endosomal trafficking and macrophage identification functions. Predominantly localized on lysosomal and endosomal membranes of monocytes and macrophages, small fraction of CD68 is displayed on cell surface. It participates in intracellular lysosomal substance transport and degradation. CD68 is a routine marker for monocyte-macrophage lineage to label tissue-resident macrophages and tumor-associated macrophages. Notably, CD68 cannot distinguish M1/M2 polarization states; low-level expression is also observed on dendritic cells and certain activated myeloid cells.
Localization
Lysosome
Research Area
免疫和传染性疾病
数据库链接
物种 Organism基因 IDSwissProt
Human 968 P34810
Mouse 12514 P31996

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

IHC
1:200-1:400
IF
1:50-1:200
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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