Anti-GFAP Mouse mAb [04D59]

Antigen-affinity-purified

Glial fibrillary acidic protein

GFAP (Glial Fibrillary Acidic Protein) is a nerve-specific protein of the intermediate filament protein family, specifically expressed in astrocytes of the central nervous system. It coregulates glial cytoskeleton construction, central nervous system development, blood-brain barrier maintenance and nerve injury response. GFAP maintains the morphological stability of astrocytes, regulates the balance of the neural microenvironment, and assists neuronal nutrient supply and signal transmission. Under pathological conditions such as brain trauma, cerebral infarction, neuroinflammation and brain tumors, astrocytes are activated and GFAP expression is significantly upregulated, serving as a specific biomarker for central nerve injury and glial activation.

Cytoskeleton