Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Tau Mouse mAb [92F92]
抗Tau小鼠单克隆抗体 [92F92]
Cat. No.
A32069
Clone No. 92F92
SynonymsTau, MAPT, MAPTL, MTBT1, TAU, Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau
详细信息 Product Information
Buffer
50% Glycerol, 0.5% BSA and 0.02% preservative in PBS (pH 7.2-7.4)
Purification
Antigen-affinity-purified
Concentration
1 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
79 kDa
Observed MW
50-85 kDa
Clonality
Monoclonal
Clone No.
92F92
抗原与靶点信息 Antigen & Target Information
Gene Name
MAPT
Protein Name
Microtubule-associated protein tau
Background
MAPT (Tau) is microtubule-associated protein that binds and stabilizes neuronal microtubules to sustain axonal cytoskeleton integrity and axonal transport. Predominantly expressed in neurons, Tau promotes microtubule assembly to maintain axonal architecture and intracellular trafficking. Tau activity is tightly modulated by phosphorylation. Hyper-phosphorylated Tau dissociates from microtubules, misfolds and aggregates into neurofibrillary tangles (NFT), hallmark pathological lesion of Alzheimer's disease and multiple tauopathies.
Localization
Cytoplasm
Research Area
神经科学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:2000
IHC
1:100-1:200
IF
1:50-1:200
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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