50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein G affinity purification
Concentration
Please check the information on the tube.
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
50 kDa
Observed MW
52 kDa
Clonality
Monoclonal
Clone No.
75F39
Isotype
IgG
抗原与靶点信息
Antigen & Target Information
Gene Name
TUBB2A
Protein Name
Beta-tubulin-2A
Domain
Full length
Background
β-Tubulin belongs to tubulin family and controls microtubule dynamics, cell division and molecular motor anchoring. β‑Tubulin forms heterodimers with α‑Tubulin and constitutes microtubule plus end, governing dynamic instability for microtubule growth and shrinkage. Multiple tissue-specific β-tubulin isoforms exist, such as neuron-specific βIII-Tubulin (Tuj1) involved in neuronal differentiation. β-Tubulin is stably expressed across most cell types and used as loading control for WB and IF. Isoform switching or mutations may confer resistance to taxane-class microtubule-targeting drugs. It is widely applied in cytoskeleton, mitosis, neuronal differentiation and anti-tumour drug resistance researches.