Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Collagen III Mouse mAb [67A18]
抗Collagen III小鼠单克隆抗体 [67A18]
Cat. No.
A33031
Clone No. 67A18
SynonymsCollagen III, Collagen-III, EDS4A, EDSVASC, PMGEDSV
详细信息 Product Information
Buffer
0.05% preservative in PBS (pH 7.2-7.4)
Purification
Affinity-purified
Concentration
1 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
138 kDa
Clonality
Monoclonal
Clone No.
67A18
Isotype
IgG
抗原与靶点信息 Antigen & Target Information
Gene Name
COL3A1
Protein Name
Collagen type-III alpha-1 chain
Domain
Full length
Background
Collagen III belongs to fibrillar collagen family and mediates extracellular-matrix assembly and tissue structural support. Synthesized and secreted mainly by fibroblasts, Collagen III assembles together with Collagen I to build soft-tissue ECM scaffold, abundantly present in skin, blood vessel, lung and liver to sustain tissue elasticity and mechanical strength. Upon tissue injury, Collagen III is robustly induced for early wound repair. Sustained excessive deposition underlies organ fibrosis and destroys tissue architecture. Within tumor microenvironment, Collagen III drives ECM remodeling and modulates tumor-cell invasion.
Localization
Secreted
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:2000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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