Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Hsp60 Mouse mAb [07B89]
抗Hsp60小鼠单克隆抗体 [07B89]
Cat. No.
A33070
Clone No. 07B89
SynonymsHsp60, HSP60, HLD4, CPN60, GROEL, HSP60, HSP65, SPG13, HSP-60, HuCHA60
详细信息 Product Information
Buffer
0.05% preservative in PBS (pH 7.2-7.4)
Purification
Affinity-purified
Concentration
1 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
60 kDa
Clonality
Monoclonal
Clone No.
07B89
Isotype
IgG
抗原与靶点信息 Antigen & Target Information
Gene Name
HSPD1
Protein Name
Heat-shock-protein-60
Domain
Full length
Background
Hsp60 (Heat shock protein 60) is a chaperonin family protein predominantly localized in mitochondrial matrix, with minor pools in cytoplasm and cell surface. It mediates folding and proper assembly of mitochondrially translated polypeptides to preserve mitochondrial architecture and oxidative respiration. Hsp60 expression rises under stress to counteract mitochondrial damage. Extracellularly released Hsp60 acts as damage-associated molecular pattern to trigger innate immune inflammation. Aberrant Hsp60 is linked to mitochondrial disorders, oncogenesis and autoimmune diseases.
Localization
Mitochondrion
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:2000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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