HRP Anti-β-Tubulin Mouse mAb [48H29]

Full length

β-Tubulin belongs to tubulin family and controls microtubule dynamics, cell division and molecular motor anchoring. β‑Tubulin forms heterodimers with α‑Tubulin and constitutes microtubule plus end, governing dynamic instability for microtubule growth and shrinkage. Multiple tissue-specific β-tubulin isoforms exist, such as neuron-specific βIII-Tubulin (Tuj1) involved in neuronal differentiation. β-Tubulin is stably expressed across most cell types and used as loading control for WB and IF. Isoform switching or mutations may confer resistance to taxane-class microtubule-targeting drugs. It is widely applied in cytoskeleton, mitosis, neuronal differentiation and anti-tumour drug resistance researches.