Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-FABP4 Rabbit mAb [41B49]
抗FABP4兔单克隆抗体 [41B49]
Cat. No.
A52004
Clone No. 41B49
SynonymsFABP4, A-FABP, A-FABP4, ARBP, aP2
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
15 kDa
Observed MW
15 kDa
Clonality
Monoclonal
Clone No.
41B49
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
FABP4
Protein Name
Fatty-acid-binding protein 4, adipocyte
Background
FABP4 (Fatty Acid Binding Protein 4, adipocyte-type fatty acid binding protein) is a small cytoplasmic transport protein of the fatty acid binding protein superfamily, encoded by the FABP4 gene with a molecular weight of approximately 15 kDa. Specifically expressed in adipocytes and macrophages, FABP4 is a hallmark protein of adipose differentiation and lipid metabolism. It primarily mediates the uptake, binding, transport, and storage regulation of long-chain fatty acids, maintaining lipid homeostasis and participating in adipocyte differentiation, tissue remodeling, and lipid signal transduction. FABP4 can be secreted extracellularly to modulate systemic metabolism. Its aberrant overexpression induces lipid accumulation, insulin resistance, inflammatory responses, and vascular endothelial damage, closely correlating with the progression of obesity, hyperlipidemia, atherosclerosis, and metabolic syndrome, and acts as a vital biomarker for lipid metabolic disorders.
Localization
Cytoplasm
Research Area
代谢
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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