Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Calreticulin Rabbit mAb [26G36]
抗Calreticulin兔单克隆抗体 [26G36]
Cat. No.
A52025
Clone No. 26G36
SynonymsCalreticulin, CRT, ERp60, GRP60, HACBP
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
48 kDa
Observed MW
55 kDa
Clonality
Monoclonal
Clone No.
26G36
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
CALR
Protein Name
Calreticulin
Background
Calreticulin is a soluble endoplasmic reticulum chaperone protein encoded by the CALR gene, serving as a key regulator of ER calcium storage and protein folding. Localized in the ER lumen, Calreticulin extensively participates in the folding, glycosylation modification and degradation of misfolded nascent proteins, cooperating with Calnexin to complete ER protein quality control. As a core calcium buffer, it precisely modulates intracellular calcium homeostasis and regulates cell proliferation, immune response, apoptosis and stress adaptation. Dysregulated Calreticulin expression triggers calcium imbalance, sustained ER stress and immune disorders, closely associated with tumor proliferation, autoimmune diseases and cardiovascular damage, and acts as a classic biomarker for ER injury.
Localization
Endoplasmic Reticulum
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
相关产品 Related Products
Anti-IL-1β Rabbit mAb [99F42]
WBIPIFELISA
Anti-Polycomb Protein SUZ12 Rabbit mAb [36G88]
WBIHCIPIFELISA
价格与规格
该产品暂未录入规格价格，请联系我们获取报价与现货情况。