50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
60 kDa
Observed MW
60 kDa
Clonality
Monoclonal
Clone No.
42C69
Isotype
IgG, Kappa
抗原与靶点信息
Antigen & Target Information
Gene Name
CAT
Protein Name
Catalase
Background
Catalase is a core heme-dependent antioxidant enzyme and a key functional protein responsible for cellular reactive oxygen species scavenging. Ubiquitously localized in cellular peroxisomes, Catalase efficiently catalyzes the decomposition of hydrogen peroxide into water and oxygen, eliminates accumulated oxidative stress products, and protects cells from ROS-induced damage, lipid peroxidation and DNA injury to maintain intracellular redox homeostasis. As an essential component of the antioxidant defense system, decreased expression or inactivation of Catalase leads to oxidative imbalance, triggering inflammatory damage, cellular senescence, metabolic disorders and malignant transformation, which is closely correlated with degenerative diseases, metabolic disorders and tumor progression.