Anti-Catalase Rabbit mAb [42C69]

抗Catalase兔单克隆抗体 [42C69]

Cat. No. A52038 Clone No. 42C69

SynonymsCatalase, CAT, Catalase-peroxidase, CAT1

Host species Rabbit
Reactivity Human, Mouse, Rat
Applications WB, IHC, IF, ELISA

详细信息 Product Information

Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
60 kDa
Observed MW
60 kDa
Clonality
Monoclonal
Clone No.
42C69
Isotype
IgG, Kappa

抗原与靶点信息 Antigen & Target Information

Gene Name
CAT
Protein Name
Catalase
Background
Catalase is a core heme-dependent antioxidant enzyme and a key functional protein responsible for cellular reactive oxygen species scavenging. Ubiquitously localized in cellular peroxisomes, Catalase efficiently catalyzes the decomposition of hydrogen peroxide into water and oxygen, eliminates accumulated oxidative stress products, and protects cells from ROS-induced damage, lipid peroxidation and DNA injury to maintain intracellular redox homeostasis. As an essential component of the antioxidant defense system, decreased expression or inactivation of Catalase leads to oxidative imbalance, triggering inflammatory damage, cellular senescence, metabolic disorders and malignant transformation, which is closely correlated with degenerative diseases, metabolic disorders and tumor progression.
Localization
Peroxisome
Research Area
代谢
数据库链接
物种 Organism基因 IDSwissProt
Human 847 P04040
Mouse P24270

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

WB
1:1000-1:5000
IHC
1:200-1:1000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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