Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-CD133 Rabbit mAb [41E34]
抗CD133兔单克隆抗体 [41E34]
Cat. No.
A52049
Clone No. 41E34
SynonymsCD133, AC133, PROM1
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
97 kDa
Observed MW
133 kDa
Clonality
Monoclonal
Clone No.
41E34
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
PROM1
Protein Name
Prominin-1
Background
CD133 (Prominin-1) is a pentaspan transmembrane glycoprotein family member responsible for plasma membrane protrusion maintenance and stem-cell-related signal regulation. Localized on microvilli and ciliary membrane protrusions, CD133 was first identified as hematopoietic stem cell marker, and later found on multiple tissue stem cells as well as cancer stem cells. CD133 sustains membrane topology, modulates cell polarity and participates in signaling vesicle trafficking. Cumulative evidence demonstrates CD133-positive cancer stem cells possess self-renewal capacity, drug-resistance and high tumorigenicity, correlating with tumor relapse and metastasis. CD133 is commonly used for isolation and characterization of cancer stem cells in brain tumor, colorectal carcinoma and other malignancies, as well as normal tissue stem cell biology investigation.
Localization
Cell membrane
Research Area
干细胞
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:20-1:100
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
相关产品 Related Products
Anti-IL-1β Rabbit mAb [99F42]
WBIPIFELISA
Anti-Polycomb Protein SUZ12 Rabbit mAb [36G88]
WBIHCIPIFELISA
价格与规格
该产品暂未录入规格价格，请联系我们获取报价与现货情况。