Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-EpCAM Rabbit mAb [86E92]
抗EpCAM兔单克隆抗体 [86E92]
Cat. No.
A52056
Clone No. 86E92
SynonymsEpCAM, TACSTD1, GA733-2, TAG-1
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
35 kDa
Observed MW
40 kDa
Clonality
Monoclonal
Clone No.
86E92
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
EPCAM
Protein Name
Epithelial cell adhesion molecule
Background
EpCAM (Epithelial cell adhesion molecule) is an epithelial adhesion molecule family member, exerting roles in epithelial intercellular adhesion, cell proliferation and signal transduction. EpCAM is predominantly expressed on epithelial cells and markedly up-regulated in diverse epithelial-origin tumor cells. Homotypic EpCAM interactions mediate weak cell-cell adhesion. Its intracellular domain can be proteolytically cleaved and translocated into nucleus to modulate transcription of cell-cycle-related genes and boost cell proliferation. During oncogenesis, EpCAM contributes to epithelial-mesenchymal transition and cancer stem-cell maintenance, correlating with tumor proliferation, invasion and poor prognosis.
Localization
Cell membrane
Research Area
癌症
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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