Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-CD3 Rabbit mAb [91F79]
抗CD3兔单克隆抗体 [91F79]
Cat. No.
A52058
Clone No. 91F79
SynonymsCD3, CD3 complex, T3 complex, TCR-CD3 complex
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
23 kDa
Observed MW
23 kDa
Clonality
Monoclonal
Clone No.
91F79
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
CD3D, CD3E, CD3G, CD247
Protein Name
T-cell receptor CD3 complex
Background
CD3 (T-cell surface glycoprotein CD3 complex) belongs to immunoglobulin superfamily and serves as the core transducer for T-cell receptor signaling. Assembled from γ, δ, ε and ζ subunits, CD3 is restrictively expressed on T-cell lineage and forms TCR-CD3 complex with T-cell receptor. Upon TCR recognition of antigen-MHC complex, intracellular ITAM motifs of CD3 become phosphorylated and relay downstream activation signals to trigger T-cell proliferation, cytokine secretion and cytotoxic effector functions. CD3 is a universal marker for all mature T lymphocytes to discriminate T-cells from other immune populations.
Localization
Cell membrane
Research Area
肿瘤免疫
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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