Anti-CD54(ICAM1) Rabbit mAb [41H66]

抗CD54(ICAM1)兔单克隆抗体 [41H66]

Cat. No. A52061 Clone No. 41H66

SynonymsCD54(ICAM1), ICAM-1 / CD54, CD54, LFA-1 ligand, BBA-1, gp150

Host species Rabbit
Reactivity Human
Applications WB, IHC, IP, IF, ELISA

详细信息 Product Information

Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
58 kDa
Observed MW
100 kDa
Clonality
Monoclonal
Clone No.
41H66
Isotype
IgG, Kappa

抗原与靶点信息 Antigen & Target Information

Gene Name
ICAM1
Protein Name
Intercellular adhesion molecule-1
Background
CD54 (Intercellular adhesion molecule-1, ICAM-1) is a member of immunoglobulin superfamily and functions in cell adhesion, immune cell recruitment and cell-to-cell interaction regulation. CD54 is present on endothelial cells, epithelial cells and immune cells with low basal expression; its abundance is strongly induced by pro-inflammatory cytokines. Serving as ligand for LFA-1 and Mac-1 integrins, CD54 mediates leukocyte-endothelial adhesion and facilitates leukocyte recruitment to inflammatory sites, and participates in antigen presentation and immune-cell crosstalk.
Localization
Cell membrane
Research Area
免疫和传染性疾病
数据库链接
物种 Organism基因 IDSwissProt
Human 3383 P05362

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

WB
1:1000-1:5000
IHC
1:100-1:200
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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