50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
58 kDa
Observed MW
100 kDa
Clonality
Monoclonal
Clone No.
41H66
Isotype
IgG, Kappa
抗原与靶点信息
Antigen & Target Information
Gene Name
ICAM1
Protein Name
Intercellular adhesion molecule-1
Background
CD54 (Intercellular adhesion molecule-1, ICAM-1) is a member of immunoglobulin superfamily and functions in cell adhesion, immune cell recruitment and cell-to-cell interaction regulation. CD54 is present on endothelial cells, epithelial cells and immune cells with low basal expression; its abundance is strongly induced by pro-inflammatory cytokines. Serving as ligand for LFA-1 and Mac-1 integrins, CD54 mediates leukocyte-endothelial adhesion and facilitates leukocyte recruitment to inflammatory sites, and participates in antigen presentation and immune-cell crosstalk.