Anti-CD68 Rabbit mAb [79E84]

抗CD68兔单克隆抗体 [79E84]

Cat. No. A52063 Clone No. 79E84

SynonymsCD68, Macrosialin, Gp110, CD68

Host species Rabbit
Reactivity Mouse, Rat
Applications WB, IHC, IF, ELISA

详细信息 Product Information

Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
37 kDa
Observed MW
100 kDa
Clonality
Monoclonal
Clone No.
79E84
Isotype
IgG, Kappa

抗原与靶点信息 Antigen & Target Information

Gene Name
CD68
Protein Name
CD68 molecule
Background
CD68 (Lysosomal-associated membrane glycoprotein CD68) belongs to mucin-like transmembrane glycoprotein family and executes lysosomal-endosomal trafficking and macrophage identification functions. Predominantly localized on lysosomal and endosomal membranes of monocytes and macrophages, small fraction of CD68 is displayed on cell surface. It participates in intracellular lysosomal substance transport and degradation. CD68 is a routine marker for monocyte-macrophage lineage to label tissue-resident macrophages and tumor-associated macrophages. Notably, CD68 cannot distinguish M1/M2 polarization states; low-level expression is also observed on dendritic cells and certain activated myeloid cells.
Localization
Lysosome
Research Area
免疫和传染性疾病
数据库链接
物种 Organism基因 IDSwissProt
Mouse 12514 P31996

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

WB
1:2000-1:10000
IHC
1:500-1:2000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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