50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
35 kDa
Observed MW
120 kDa
Clonality
Monoclonal
Clone No.
26F92
Isotype
IgG, Kappa
抗原与靶点信息
Antigen & Target Information
Gene Name
CD68
Protein Name
CD68 molecule
Background
CD68 (Lysosomal-associated membrane glycoprotein CD68) belongs to mucin-like transmembrane glycoprotein family and executes lysosomal-endosomal trafficking and macrophage identification functions. Predominantly localized on lysosomal and endosomal membranes of monocytes and macrophages, small fraction of CD68 is displayed on cell surface. It participates in intracellular lysosomal substance transport and degradation. CD68 is a routine marker for monocyte-macrophage lineage to label tissue-resident macrophages and tumor-associated macrophages. Notably, CD68 cannot distinguish M1/M2 polarization states; low-level expression is also observed on dendritic cells and certain activated myeloid cells.