Anti-CD81 Rabbit mAb [20H84]

抗CD81兔单克隆抗体 [20H84]

Cat. No. A52066 Clone No. 20H84

SynonymsCD81, TAPA-1, SNAT, ASGM1W, 5B11

Host species Rabbit
Reactivity Human, Mouse, Rat
Applications WB, IHC, IF, ELISA

详细信息 Product Information

Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
26 kDa
Observed MW
22 kDa
Clonality
Monoclonal
Clone No.
20H84
Isotype
IgG, Kappa

抗原与靶点信息 Antigen & Target Information

Gene Name
CD81
Protein Name
CD81 molecule
Background
CD81 (Cluster of differentiation 81, TAPA-1) is a tetraspanin superfamily member responsible for membrane complex assembly and immune-cell signal modulation. Broadly distributed across cell types, CD81 is abundant in B-cells, T-cells, dendritic cells and hepatocytes. As a core tetraspanin network component, it assembles with CD19-CD21 to form B-cell co-receptor complex and regulates B-cell development and activation. It also modulates T-cell activation, spermatogenesis and viral entry, serving as a critical receptor for HCV infection. CD81 is embedded within exosome membrane and acts as a well-accepted exosome reference marker.
Localization
Cell membrane
Research Area
肿瘤免疫
数据库链接
物种 Organism基因 IDSwissProt
Human 975 P60033
Mouse 12520 P35762

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

WB
1:2000-1:10000
IHC
1:200-1:1000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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