50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
26 kDa
Observed MW
22 kDa
Clonality
Monoclonal
Clone No.
20H84
Isotype
IgG, Kappa
抗原与靶点信息
Antigen & Target Information
Gene Name
CD81
Protein Name
CD81 molecule
Background
CD81 (Cluster of differentiation 81, TAPA-1) is a tetraspanin superfamily member responsible for membrane complex assembly and immune-cell signal modulation. Broadly distributed across cell types, CD81 is abundant in B-cells, T-cells, dendritic cells and hepatocytes. As a core tetraspanin network component, it assembles with CD19-CD21 to form B-cell co-receptor complex and regulates B-cell development and activation. It also modulates T-cell activation, spermatogenesis and viral entry, serving as a critical receptor for HCV infection. CD81 is embedded within exosome membrane and acts as a well-accepted exosome reference marker.