Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Chromogranin A Rabbit mAb [95F33]
抗Chromogranin A兔单克隆抗体 [95F33]
Cat. No.
A52077
Clone No. 95F33
SynonymsChromogranin A, secretogranin-I, granin family protein
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
51 kDa
Observed MW
80 kDa
Clonality
Monoclonal
Clone No.
95F33
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
CHGA
Protein Name
Chromogranin-A
Background
Chromogranin A (CgA) belongs to chromogranin family and regulates neuroendocrine granule storage as well as hormone processing and secretion. CgA is packaged within secretory vesicles of neuroendocrine cells and co-released together with hormones. Proteolytic cleavage of CgA yields multiple bioactive peptides modulating hormone release, vascular homeostasis and inflammatory responses. CgA is abundant in pituitary, adrenal medulla and gastrointestinal neuroendocrine cells. It is highly expressed in neuroendocrine tumors and represents a critical diagnostic biomarker. Circulating CgA also serves as auxiliary serological indicator for certain neuroendocrine neoplasms.
Localization
Secreted
Research Area
癌症
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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