Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-CIRBP Rabbit mAb [74B07]
抗CIRBP兔单克隆抗体 [74B07]
Cat. No.
A52078
Clone No. 74B07
SynonymsCIRBP, p32, cold-shock domain protein CIRP, RNA-binding protein p32
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
19 kDa
Observed MW
19 kDa
Clonality
Monoclonal
Clone No.
74B07
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
CIRBP
Protein Name
Cold-inducible RNA-binding protein
Background
CIRBP (Cold-inducible RNA-binding protein) is an RNA-binding protein mediating post-transcriptional RNA regulation and cellular stress response. CIRBP expression is induced upon cold exposure, hypoxia and oxidative stress. Localized in nucleus and cytoplasm, CIRBP binds target mRNAs to modulate mRNA stability and translation efficiency and facilitate cellular stress adaptation. Under homeostatic conditions, it participates in cell proliferation and cell-cycle control. Upon stress, CIRBP can be secreted extracellularly as damage-associated molecular pattern to shape inflammatory responses.
Localization
Nucleus
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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