50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
192 kDa
Observed MW
180 kDa
Clonality
Monoclonal
Clone No.
21F39
Isotype
IgG, Kappa
抗原与靶点信息
Antigen & Target Information
Gene Name
CLTC
Protein Name
Clathrin heavy chain 1
Background
Clathrin Heavy Chain belongs to clathrin scaffold-protein family and mediates clathrin-dependent endocytosis and vesicular trafficking. Clathrin heavy and light chains assemble into triskelion complexes, which form clathrin coats beneath plasma membrane to drive endocytosis of membrane receptors and ligands, and also support vesicle transport from Golgi apparatus to endosomes. This pathway controls receptor recycling, ligand internalization and transmembrane substance trafficking to shape cell signaling and nutrient uptake.