Anti-Clathrin (Heavy chain) Rabbit mAb [21F39]

抗Clathrin (Heavy chain)兔单克隆抗体 [21F39]

Cat. No. A52081 Clone No. 21F39

SynonymsClathrin (Heavy chain), Clathrin HC, Clathrin heavy chain, p190, CLTH1

Host species Rabbit
Reactivity Human, Mouse, Rat
Applications WB, IHC, IF, ELISA

详细信息 Product Information

Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
192 kDa
Observed MW
180 kDa
Clonality
Monoclonal
Clone No.
21F39
Isotype
IgG, Kappa

抗原与靶点信息 Antigen & Target Information

Gene Name
CLTC
Protein Name
Clathrin heavy chain 1
Background
Clathrin Heavy Chain belongs to clathrin scaffold-protein family and mediates clathrin-dependent endocytosis and vesicular trafficking. Clathrin heavy and light chains assemble into triskelion complexes, which form clathrin coats beneath plasma membrane to drive endocytosis of membrane receptors and ligands, and also support vesicle transport from Golgi apparatus to endosomes. This pathway controls receptor recycling, ligand internalization and transmembrane substance trafficking to shape cell signaling and nutrient uptake.
Localization
Cytoplasm
Research Area
细胞生物学
数据库链接
物种 Organism基因 IDSwissProt
Human 1213 Q00610

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

WB
1:500-1:2000
IHC
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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