Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Claudin 1 Rabbit mAb [17D42]
抗Claudin 1兔单克隆抗体 [17D42]
Cat. No.
A52082
Clone No. 17D42
SynonymsClaudin 1, Claudin-1, CLJ, occludin-like protein, ZO-1-interacting protein
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
22 kDa
Observed MW
19 kDa
Clonality
Monoclonal
Clone No.
17D42
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
CLDN1
Protein Name
Claudin-1
Background
Claudin 1 belongs to Claudin tight-junction protein family and builds epithelial tight junctions to sustain tissue barrier function. Localized at tight-junction sites of epithelial and endothelial cells, Claudin1 engages in homotypic or heterotypic interactions with Claudin molecules on adjacent cells, constitutes tight-junction barrier and controls paracellular permeability to preserve epithelial integrity. Claudin1 also modulates cell proliferation and migration signaling. Its dysregulation disrupts epithelial barrier and contributes to tumor invasion and metastasis.
Localization
Cell membrane
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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