Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-c-Myc Rabbit mAb [49B27]
抗c-Myc兔单克隆抗体 [49B27]
Cat. No.
A52083
Clone No. 49B27
Synonymsc-Myc, p62, v-myc avian myelocytomatosis viral oncogene homolog
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
48 kDa
Observed MW
60 kDa
Clonality
Monoclonal
Clone No.
49B27
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
MYC
Protein Name
MYC proto-oncogene, bHLH transcription factor
Background
c-Myc (Proto-oncogene c-Myc) belongs to MYC bHLH-LZ transcription-factor family and drives transcriptional reprogramming for cell proliferation and metabolism. c-Myc heterodimerizes with Max, binds E-box motifs and modulates transcription of thousands of target genes governing cell-cycle progression, ribosome biogenesis, glycolipid metabolism and apoptosis. c-Myc is tightly regulated at transcriptional and protein-stability levels. Gene amplification or transcriptional activation in tumors causes c-Myc accumulation, driving malignant proliferation and metabolic reprogramming.
Localization
Nucleus
Research Area
癌症
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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