50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
26 kDa
Observed MW
21 kDa
Clonality
Monoclonal
Clone No.
24C08
Isotype
IgG, Kappa
抗原与靶点信息
Antigen & Target Information
Gene Name
MT-CO2
Protein Name
Mitochondrially-encoded cytochrome c oxidase subunit 2
Background
MTCO2 (Mitochondrial cytochrome c oxidase subunit 2) is a subunit of mitochondrial respiratory chain complex IV and mediates electron-transfer during mitochondrial oxidative phosphorylation. Encoded by mitochondrial DNA, MTCO2 localizes to inner mitochondrial membrane and serves as a core component of complex IV. It catalyzes electron transfer from cytochrome c to molecular oxygen to fuel ATP production. MTCO2 abundance mirrors mitochondrial respiratory capacity. Its expression decreases upon mitochondrial damage, oxidative stress and hypoxia, linking to energy-metabolism dysfunction and apoptosis activation.