Anti-MTCO2 Rabbit mAb [24C08]

抗MTCO2兔单克隆抗体 [24C08]

Cat. No. A52087 Clone No. 24C08

SynonymsMTCO2, MT-CO2, COX2, Cytochrome c oxidase subunit II, COXII

Host species Rabbit
Reactivity Human
Applications WB, IHC, IP, IF, ELISA

详细信息 Product Information

Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
26 kDa
Observed MW
21 kDa
Clonality
Monoclonal
Clone No.
24C08
Isotype
IgG, Kappa

抗原与靶点信息 Antigen & Target Information

Gene Name
MT-CO2
Protein Name
Mitochondrially-encoded cytochrome c oxidase subunit 2
Background
MTCO2 (Mitochondrial cytochrome c oxidase subunit 2) is a subunit of mitochondrial respiratory chain complex IV and mediates electron-transfer during mitochondrial oxidative phosphorylation. Encoded by mitochondrial DNA, MTCO2 localizes to inner mitochondrial membrane and serves as a core component of complex IV. It catalyzes electron transfer from cytochrome c to molecular oxygen to fuel ATP production. MTCO2 abundance mirrors mitochondrial respiratory capacity. Its expression decreases upon mitochondrial damage, oxidative stress and hypoxia, linking to energy-metabolism dysfunction and apoptosis activation.
Localization
Mitochondrion
Research Area
代谢
数据库链接
物种 Organism基因 IDSwissProt
Human 4513 P00403

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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