Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-CTGF Rabbit mAb [07F57]
抗CTGF兔单克隆抗体 [07F57]
Cat. No.
A52089
Clone No. 07F57
SynonymsCTGF, CCN2, Novel cysteine-rich protein, IGFBP-related protein 2
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
38 kDa
Observed MW
38 kDa
Clonality
Monoclonal
Clone No.
07F57
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
CTGF
Protein Name
Connective tissue growth factor
Background
CTGF (Connective tissue growth factor, CCN2) is a secreted extracellular-matrix protein of CCN family, regulating ECM remodeling, cell proliferation-migration and fibrogenesis. Robustly induced by pro-fibrotic cues such as TGF-β, secreted CTGF drives fibroblast activation and boosts synthesis-deposition of collagens and other ECM components to promote fibrosis. It also modulates cell adhesion, angiogenesis and epithelial-mesenchymal transition. CTGF mediates tissue remodelling during wound repair, while sustained aberrant overexpression causes organ fibrosis. Within tumor microenvironment, CTGF shapes stromal remodelling and influences tumor proliferation and invasion. CTGF serves as a central fibrotic marker for organ-fibrosis, wound-repair and tumor-microenvironment researches.
Localization
Secreted
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:500-1:2000
IP
1:50-1:200
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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