Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Cytokeratin 10 Rabbit mAb [49B68]
抗Cytokeratin 10兔单克隆抗体 [49B68]
Cat. No.
A52094
Clone No. 49B68
SynonymsCytokeratin 10, CK-10, K10, type I cytoskeletal keratin 10
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
59 kDa
Observed MW
59 kDa
Clonality
Monoclonal
Clone No.
49B68
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
KRT10
Protein Name
Keratin-10
Background
Cytokeratin 10 (CK10) belongs to type-I intermediate-filament protein family and provides cytoskeletal support for epithelial cells against mechanical stress. Predominantly expressed in terminally-differentiated squamous epithelial cells, CK10 heterodimerizes with CK1 to assemble keratin intermediate filaments, sustaining cellular morphology and mechanical resistance. CK10 is markedly up-regulated during epidermal keratinocyte differentiation and acts as a marker for mature epidermal differentiation. Dysregulated CK10 associates with cutaneous hyperkeratosis disorders; its expression is altered in squamous-origin tumours.
Localization
Cytoskeleton
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:2000-1:10000
IHC
1:200-1:1000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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