Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Cytokeratin 14 Rabbit mAb [01H52]
抗Cytokeratin 14兔单克隆抗体 [01H52]
Cat. No.
A52095
Clone No. 01H52
SynonymsCytokeratin 14, CK-14, K14, type I cytoskeletal keratin 14
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
52 kDa
Observed MW
52 kDa
Clonality
Monoclonal
Clone No.
01H52
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
KRT14
Protein Name
Keratin-14
Background
Cytokeratin 14 (CK14) belongs to type-I intermediate-filament family and builds epithelial cytoskeleton to sustain basal-epithelial and stem-cell properties. Predominantly located within basal-layer cells of stratified squamous epithelia, CK14 pairs with CK5 to assemble keratin intermediate filaments and preserve basal-cell cytoskeletal integrity. CK14 serves as canonical marker for epidermal basal stem-progenitor cells and participates in cutaneous wound repair. Germline mutations in CK14 cause blistering skin disorders. CK14 remains highly expressed in squamous-cell carcinoma and certain basal-cell neoplasms.
Localization
Cytoskeleton
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:2000-1:10000
IHC
1:200-1:1000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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