Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Cytokeratin 20 Rabbit mAb [11D43]
抗Cytokeratin 20兔单克隆抗体 [11D43]
Cat. No.
A52098
Clone No. 11D43
SynonymsCytokeratin 20, CK-20, K20, CK20, type I cytokeratin 20
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
49 kDa
Observed MW
49 kDa
Clonality
Monoclonal
Clone No.
11D43
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
KRT20
Protein Name
Keratin-20
Background
Cytokeratin 20 (CK20) belongs to type-I intermediate-filament family and provides cytoskeletal support for specific epithelial subsets. CK20 exhibits prominent tissue specificity, mainly localizing to gastrointestinal mucosa, urothelium and Merkel cells. It remains positive in colorectal carcinoma, selected urothelial neoplasms and Merkel-cell carcinoma, whereas most non-gastrointestinal adenocarcinomas are CK20-negative, rendering CK20 a vital marker for pathological differential diagnosis. Clinical IHC CK20 staining assists discrimination of gastrointestinal-origin tumours from other adenocarcinomas and aids primary-tumour tracing.
Localization
Cytoskeleton
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:2000-1:10000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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