Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Cytokeratin 5 Rabbit mAb [91H69]
抗Cytokeratin 5兔单克隆抗体 [91H69]
Cat. No.
A52099
Clone No. 91H69
SynonymsCytokeratin 5, CK-5, K5, type II cytoskeletal keratin 5
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
62 kDa
Observed MW
62 kDa
Clonality
Monoclonal
Clone No.
91H69
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
KRT5
Protein Name
Keratin-5
Background
Cytokeratin 5 (CK5) belongs to type-II intermediate-filament family and supports cytoskeleton of stratified epithelia. Predominantly expressed in basal-layer cells of stratified squamous epithelia, CK5 pairs with CK14 to assemble keratin intermediate filaments and maintain basal-cell mechanical stability. CK5 serves as an epidermal basal-stem-cell marker and participates in cutaneous wound repair; pathogenic mutations cause blistering skin diseases. CK5 is highly expressed in tumour subsets including triple-negative breast cancer and lung squamous-cell carcinoma for molecular subtyping.
Localization
Cytoskeleton
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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