Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Cytokeratin 7 Rabbit mAb [38F84]
抗Cytokeratin 7兔单克隆抗体 [38F84]
Cat. No.
A52100
Clone No. 38F84
SynonymsCytokeratin 7, CK-7, K7, CK7, type II cytokeratin 7
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
51 kDa
Observed MW
55 kDa
Clonality
Monoclonal
Clone No.
38F84
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
KRT7
Protein Name
Keratin-7
Background
Cytokeratin 7 (CK7) belongs to type-II intermediate-filament family and sustains glandular-epithelial cytoskeleton. CK7 is mainly detected in glandular and transitional epithelia of lung, breast, biliary tract and ovary, frequently applied together with CK19. It is commonly positive in lung adenocarcinoma, ovarian carcinoma and cholangiocarcinoma, while colorectal carcinoma is usually CK7-negative, making CK7 an important marker for primary-tumour-origin discrimination. Clinical IHC combines CK7 and CK20 profiles to distinguish adenocarcinomas derived from gastrointestinal tract, lung, breast and ovary.
Localization
Cytoskeleton
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:1000-1:2000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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