Anti-FOXO1A Rabbit mAb [40G62]

Protein A affinity purification

Fork-head box O1

FOXO1A (Forkhead Box Protein O1A) is a core member of the forkhead box transcription factor family, widely distributed in human liver, muscle, pancreas and tumor cells. It primarily participates in the regulation of cell cycle, glucose and lipid metabolism, oxidative stress response and cell apoptosis. By binding to the promoters of downstream target genes, FOXO1A modulates cell proliferation, differentiation, senescence and metabolic homeostasis to sustain normal physiological functions. Abnormal expression or functional inactivation of FOXO1A leads to cell cycle disorder, metabolic imbalance and accumulated oxidative damage, further inducing liver cancer, diabetes, muscular atrophy and various malignant tumors. As a critical regulatory target for tumors and metabolic diseases, FOXO1A can be specifically targeted by anti-FOXO1A rabbit monoclonal antibodies to regulate its transcriptional activity, correct abnormal cell metabolism and proliferation, and inhibit malignant growth of tumor cells, possessing important research and clinical application value.

Cytoplasm, Nucleus