Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-FXR1 Rabbit mAb [63F54]
抗FXR1兔单克隆抗体 [63F54]
Cat. No.
A52124
Clone No. 63F54
SynonymsFXR1, FMR2, FRAXE, p150, fragile X-related protein
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
70 kDa
Observed MW
70-84 kDa
Clonality
Monoclonal
Clone No.
63F54
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
FXR1
Protein Name
Fragile X-related protein-1
Background
FXR1 (Fragile X Mental Retardation-Related Protein 1) is an important member of the RNA-binding protein family, widely expressed in the nervous system, muscle tissues and germ cells. It is mainly involved in post-transcriptional RNA regulation, cell proliferation and differentiation, neural development and muscle homeostasis maintenance. By binding to target RNA, FXR1 regulates mRNA splicing, translation and stability, and participates in key physiological processes such as nerve cell maturation and muscle cell differentiation. Abnormal expression or mutation of FXR1 disrupts RNA metabolic balance, leads to abnormal neural development and muscle dysplasia, and drives the proliferation, invasion and metastasis of tumor cells, with aberrant overexpression in lung cancer, gastric cancer and other tumors.
Localization
Cytoplasm
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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