50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
76 kDa
Observed MW
100 kDa
Clonality
Monoclonal
Clone No.
14A92
Isotype
IgG, Kappa
抗原与靶点信息
Antigen & Target Information
Protein Name
Beta-galactosidase
Background
β-Galactosidase is a key hydrolase belonging to the glycoside hydrolase family, widely present in human tissues and cells. It coregulates cellular glucose metabolism, lysosomal degradation, cell senescence and organelle homeostasis. This enzyme specifically hydrolyzes β-galactoside bonds and decomposes lactose and glycoside complexes to supply energy for cell metabolism, and serves as a classic biomarker of cellular senescence, participating in the recognition and clearance of senescent cells. Its activity is significantly upregulated and abnormally accumulated in senescent, damaged and cancerous cells.