Anti-β-Galactosidase Rabbit mAb [14A92]

抗β-Galactosidase兔单克隆抗体 [14A92]

Cat. No. A52125 Clone No. 14A92

Synonymsβ-Galactosidase, lacZ, beta-Gal, β-galactosidase (reporter enzyme, no specific gene symbol)

Host species Rabbit
Reactivity Human, Mouse, Rat
Applications WB, IHC, IF, ELISA

详细信息 Product Information

Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
76 kDa
Observed MW
100 kDa
Clonality
Monoclonal
Clone No.
14A92
Isotype
IgG, Kappa

抗原与靶点信息 Antigen & Target Information

Protein Name
Beta-galactosidase
Background
β-Galactosidase is a key hydrolase belonging to the glycoside hydrolase family, widely present in human tissues and cells. It coregulates cellular glucose metabolism, lysosomal degradation, cell senescence and organelle homeostasis. This enzyme specifically hydrolyzes β-galactoside bonds and decomposes lactose and glycoside complexes to supply energy for cell metabolism, and serves as a classic biomarker of cellular senescence, participating in the recognition and clearance of senescent cells. Its activity is significantly upregulated and abnormally accumulated in senescent, damaged and cancerous cells.
Localization
Lysosome
Research Area
细胞生物学
数据库链接
物种 Organism基因 IDSwissProt
Human 2720 P16278
Mouse P23780

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

WB
1:1000-1:5000
IHC
1:2000-1:10000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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