Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-GAP43 Rabbit mAb [73A65]
抗GAP43兔单克隆抗体 [73A65]
Cat. No.
A52126
Clone No. 73A65
SynonymsGAP43, GAP-43, B-50, GAP-43, F-24, neuromodulin
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
25 kDa
Observed MW
48 kDa
Clonality
Monoclonal
Clone No.
73A65
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
GAP43
Protein Name
Growth-associated protein-43
Background
GAP43 (Growth-Associated Protein 43) is a core molecule of the nerve-specific phosphorylated protein family, specifically expressed in neurons of the central and peripheral nervous systems. It mainly participates in neurite growth, synaptic remodeling, neural development and nerve injury repair. By regulating neuronal cytoskeleton remodeling, GAP43 promotes axon extension and synaptic structure renewal, maintaining normal nervous system development and nerve signal conduction. Its expression is significantly upregulated under pathological conditions such as nerve injury, cerebral ischemia and neuroinflammation to mediate nerve repair and regeneration, while abnormal inhibition of GAP43 leads to neural dysplasia and nerve repair disorders.
Localization
Cell membrane
Research Area
神经科学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:2000-1:10000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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