Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-GFAP Rabbit mAb [55E22]
抗GFAP兔单克隆抗体 [55E22]
Cat. No.
A52130
Clone No. 55E22
SynonymsGFAP, Glial fibrillary acidic protein
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
50 kDa
Observed MW
50 kDa
Clonality
Monoclonal
Clone No.
55E22
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
GFAP
Protein Name
Glial fibrillary acidic protein
Background
GFAP (Glial Fibrillary Acidic Protein) is a nerve-specific protein of the intermediate filament protein family, specifically expressed in astrocytes of the central nervous system. It coregulates glial cytoskeleton construction, central nervous system development, blood-brain barrier maintenance and nerve injury response. GFAP maintains the morphological stability of astrocytes, regulates the balance of the neural microenvironment, and assists neuronal nutrient supply and signal transmission. Under pathological conditions such as brain trauma, cerebral infarction, neuroinflammation and brain tumors, astrocytes are activated and GFAP expression is significantly upregulated, serving as a specific biomarker for central nerve injury and glial activation.
Localization
Cytoskeleton
Research Area
神经科学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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