Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-NOX2 Rabbit mAb [98D08]
抗NOX2兔单克隆抗体 [98D08]
Cat. No.
A52135
Clone No. 98D08
SynonymsNOX2, gp91phox, NOX2, NADPH oxidase 2
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
65 kDa
Observed MW
65 kDa
Clonality
Monoclonal
Clone No.
98D08
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
CYBB
Protein Name
NADPH oxidase-2
Background
NOX2 (NADPH Oxidase 2) is a key subtype protein of the NADPH oxidase family, mainly expressed in immune and vascular-related cells such as macrophages, neutrophils and vascular endothelial cells. It coregulates in vivo reactive oxygen species (ROS) generation, inflammatory response, immune defense and oxidative stress. NOX2 catalyzes NADPH oxidation to produce ROS, mediates antibacterial immune defense and regulates the activation of inflammatory signaling pathways. Excessive abnormal activation of NOX2 causes massive ROS accumulation, triggers oxidative damage and inflammatory cascade reactions, continuously driving the progression of vascular inflammation, atherosclerosis, pulmonary inflammation and autoimmune diseases, and promoting tumor microenvironment inflammatory remodeling.
Localization
Cell membrane
Research Area
免疫和传染性疾病
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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