Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Hsp60 Rabbit mAb [81F26]
抗Hsp60兔单克隆抗体 [81F26]
Cat. No.
A52175
Clone No. 81F26
SynonymsHsp60, HSP60, HSP60alpha, HSPC10, Mitochondrial chaperonin
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
60 kDa
Observed MW
60 kDa
Clonality
Monoclonal
Clone No.
81F26
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
HSPD1
Protein Name
Heat-shock protein-60
Background
Hsp60 (Heat shock protein 60) is a chaperonin family protein predominantly localized in mitochondrial matrix, with minor pools in cytoplasm and cell surface. It mediates folding and proper assembly of mitochondrially translated polypeptides to preserve mitochondrial architecture and oxidative respiration. Hsp60 expression rises under stress to counteract mitochondrial damage. Extracellularly released Hsp60 acts as damage-associated molecular pattern to trigger innate immune inflammation. Aberrant Hsp60 is linked to mitochondrial disorders, oncogenesis and autoimmune diseases.
Localization
Mitochondrion
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:1000-1:4000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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