Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Hsp90 Rabbit mAb [32H23]
抗Hsp90兔单克隆抗体 [32H23]
Cat. No.
A52177
Clone No. 32H23
SynonymsHsp90, HSP90, HSP90alpha, HSP82, p84, HSPC3
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
85 kDa
Observed MW
85 kDa
Clonality
Monoclonal
Clone No.
32H23
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
HSP90AA1
Protein Name
Heat-shock protein-90 alpha
Background
Hsp90 (Heat shock protein 90) is an Hsp90-family molecular chaperone abundant in cytoplasm, with isoforms present in ER and mitochondria. It orchestrates folding and conformational stabilization of client proteins including kinases and transcription factors to enable their functional maturation. Hsp90 governs signaling cascades controlling cell proliferation, survival and migration. Many oncogenic drivers rely on Hsp90 for stability; Hsp90 up-regulation sustains malignant phenotypes in tumors, making Hsp90 a promising anti-cancer drug target.
Localization
Cytoplasm
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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