Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-IFITM3 Rabbit mAb [40E33]
抗IFITM3兔单克隆抗体 [40E33]
Cat. No.
A52180
Clone No. 40E33
SynonymsIFITM3, CD226L, IMDM
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
14 kDa
Observed MW
14 kDa
Clonality
Monoclonal
Clone No.
40E33
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
IFITM3
Protein Name
Interferon-induced transmembrane protein-3
Background
IFITM3 (Interferon-induced transmembrane protein 3) is an IFITM-family transmembrane protein residing on endosomes, lysosomes and plasma membrane. It mediates host antiviral immunity: transcription is strongly induced by type-I interferons, and IFITM3 blocks entry of numerous enveloped viruses by impairing viral-host membrane fusion within endosomes. It also modulates intracellular membrane trafficking; loss-of-function confers higher susceptibility to viral infection. Besides antiviral roles, IFITM3 participates in cell proliferation and tumor progression with altered expression in certain cancers.
Localization
Cell membrane
Research Area
免疫和传染性疾病
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
相关产品 Related Products
Anti-IL-1β Rabbit mAb [99F42]
WBIPIFELISA
Anti-Polycomb Protein SUZ12 Rabbit mAb [36G88]
WBIHCIPIFELISA
价格与规格
该产品暂未录入规格价格，请联系我们获取报价与现货情况。