50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
21 kDa
Observed MW
21 kDa
Clonality
Monoclonal
Clone No.
10H50
Isotype
IgG, Kappa
抗原与靶点信息
Antigen & Target Information
Gene Name
IL10
Protein Name
Interleukin-10
Background
IL-10 (Interleukin-10) is an IL-10-family cytokine mainly secreted by T regulatory cells, macrophages and other immune populations. It serves as a master anti-inflammatory immunomodulator, repressing pro-inflammatory cytokine production and dampening antigen presentation to restrain excessive inflammatory responses and host tissue damage. IL-10 preserves immune homeostasis; its deficiency leads to severe inflammatory and autoimmune pathologies. Within tumor microenvironment, IL-10 can suppress anti-tumor immunity and facilitate immune escape.