Anti-IL-10 Rabbit mAb [10H50]

抗IL-10兔单克隆抗体 [10H50]

Cat. No. A52182 Clone No. 10H50

SynonymsIL-10, CSIF, HGF-B2, BCGF-II

Host species Rabbit
Reactivity Human, Mouse, Rat
Applications WB, IF, ELISA

详细信息 Product Information

Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
21 kDa
Observed MW
21 kDa
Clonality
Monoclonal
Clone No.
10H50
Isotype
IgG, Kappa

抗原与靶点信息 Antigen & Target Information

Gene Name
IL10
Protein Name
Interleukin-10
Background
IL-10 (Interleukin-10) is an IL-10-family cytokine mainly secreted by T regulatory cells, macrophages and other immune populations. It serves as a master anti-inflammatory immunomodulator, repressing pro-inflammatory cytokine production and dampening antigen presentation to restrain excessive inflammatory responses and host tissue damage. IL-10 preserves immune homeostasis; its deficiency leads to severe inflammatory and autoimmune pathologies. Within tumor microenvironment, IL-10 can suppress anti-tumor immunity and facilitate immune escape.
Localization
Secreted
Research Area
免疫和传染性疾病
数据库链接
物种 Organism基因 IDSwissProt
Human 3586 P22301
Mouse P18893

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

WB
1:2000-1:10000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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