Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-IL-1β Rabbit mAb [99F42]
抗IL-1β兔单克隆抗体 [99F42]
Cat. No.
A52186
Clone No. 99F42
SynonymsIL-1β, IL-1, IL-F1, LPSRF
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
31 kDa
Observed MW
31 kDa
Clonality
Monoclonal
Clone No.
99F42
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
IL1B
Protein Name
Interleukin-1 beta
Background
IL-1β (Interleukin-1 beta) is a member of IL-1 pro-inflammatory cytokine superfamily. Inactive pro-IL-1β accumulates in cytoplasm; mature secreted IL-1β is generated via caspase-1 cleavage upon inflammasome activation. As a potent pro-inflammatory mediator, IL-1β induces diverse inflammatory mediators, recruits immune cells and initiates local and systemic inflammation. It mediates host defense against pathogens, whereas sustained inappropriate release drives autoimmunity, metabolic inflammation and tumor-microenvironment remodeling.
Localization
Secreted
Research Area
免疫和传染性疾病
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:2000-1:10000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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