50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
87 kDa
Observed MW
100 kDa
Clonality
Monoclonal
Clone No.
25F24
Isotype
IgG, Kappa
抗原与靶点信息
Antigen & Target Information
Gene Name
ITGB3
Protein Name
Integrin subunit beta-3
Background
Integrin β3 is a β-family transmembrane integrin subunit, predominantly pairing with αIIb or αv subunits. It mediates cell adhesion and signal transduction, supporting platelet aggregation, cell-matrix attachment, cell migration and angiogenesis. Integrin β3 is expressed in platelets, endothelial cells and subsets of tumor cells. The αvβ3 heterodimer is enriched on neovasculature and drives tumor angiogenesis and metastasis.