Anti-Integrin β-3 Rabbit mAb [25F24]

抗Integrin β-3兔单克隆抗体 [25F24]

Cat. No. A52193 Clone No. 25F24

SynonymsIntegrin β-3, CD61, GPIIb, Integrin beta-3

Host species Rabbit
Reactivity Human, Mouse, Rat
Applications WB, IHC, IP, IF, ELISA

详细信息 Product Information

Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
87 kDa
Observed MW
100 kDa
Clonality
Monoclonal
Clone No.
25F24
Isotype
IgG, Kappa

抗原与靶点信息 Antigen & Target Information

Gene Name
ITGB3
Protein Name
Integrin subunit beta-3
Background
Integrin β3 is a β-family transmembrane integrin subunit, predominantly pairing with αIIb or αv subunits. It mediates cell adhesion and signal transduction, supporting platelet aggregation, cell-matrix attachment, cell migration and angiogenesis. Integrin β3 is expressed in platelets, endothelial cells and subsets of tumor cells. The αvβ3 heterodimer is enriched on neovasculature and drives tumor angiogenesis and metastasis.
Localization
Cell membrane
Research Area
细胞生物学
数据库链接
物种 Organism基因 IDSwissProt
Human 3690 P05106
Mouse 16416 O54890

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

WB
1:500-1:2000
IHC
1:1000-1:4000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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