Anti-ISG15 Rabbit mAb [75A64]

抗ISG15兔单克隆抗体 [75A64]

Cat. No. A52196 Clone No. 75A64

SynonymsISG15, ISG-15, LA-I

Host species Rabbit
Reactivity Human
Applications WB, IF, ELISA

详细信息 Product Information

Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
18 kDa
Observed MW
18 kDa
Clonality
Monoclonal
Clone No.
75A64
Isotype
IgG, Kappa

抗原与靶点信息 Antigen & Target Information

Gene Name
ISG15
Protein Name
Interferon-stimulated gene-15
Background
ISG15 (Interferon-stimulated gene 15) is a ubiquitin-like modifier whose expression is potently induced by type-I interferons. It mediates ISGylation, a post-translational modification that covalently conjugates target proteins to alter their stability, localization and function for host antiviral innate defense. ISG15 restricts replication of diverse viruses; unconjugated free ISG15 exerts cytokine-like activities to tune immune-cell responses. Dysregulated ISG15 is associated with viral infection, inflammation and cancer.
Localization
Cytoplasm
Research Area
免疫和传染性疾病
数据库链接
物种 Organism基因 IDSwissProt
Human 9636 P05161

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

WB
1:500-1:2000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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