Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-JNK1/2/3 Rabbit mAb [38B61]
抗JNK1/2/3兔单克隆抗体 [38B61]
Cat. No.
A52198
Clone No. 38B61
SynonymsJNK1/2/3, JNK1/JNK2/JNK3, SAPK1/SAPK2/SAPK3
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
48 kDa, 53 kDa
Observed MW
48 kDa, 53 kDa
Clonality
Monoclonal
Clone No.
38B61
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
MAPK8, MAPK9, MAPK10
Protein Name
c-Jun N-terminal kinase 1/2/3
Background
JNK1/2/3 (c-Jun N-terminal kinase 1/2/3) are serine-threonine kinases belonging to MAPK (mitogen-activated protein kinase) family. They transduce stress signals: upon stimulation by cytokines, oxidative stress or DNA damage, JNKs become phosphorylated and activated, translocate to nucleus and phosphorylate transcription factors such as c-Jun to reprogram gene expression. JNK signaling modulates apoptosis, proliferation and inflammation. Isoforms show tissue preference; JNK3 is highly enriched in nervous system. Excessive JNK activation contributes to neurodegeneration, inflammation and cancer.
Localization
Cytoplasm, Nucleus
Research Area
免疫和传染性疾病
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:2000-1:10000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
相关产品 Related Products
Anti-IL-1β Rabbit mAb [99F42]
WBIPIFELISA
Anti-Polycomb Protein SUZ12 Rabbit mAb [36G88]
WBIHCIPIFELISA
价格与规格
该产品暂未录入规格价格，请联系我们获取报价与现货情况。