50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
55 kDa
Observed MW
60 kDa
Clonality
Monoclonal
Clone No.
09G15
Isotype
IgG, Kappa
抗原与靶点信息
Antigen & Target Information
Gene Name
KLF4
Protein Name
Kruppel-like factor-4
Background
KLF4 (Kruppel-like factor 4) is a nuclear zinc-finger transcription factor of KLF family. It acts as dual-function transcriptional regulator, activating or repressing target genes to govern cell-cycle control, cellular differentiation, epithelial-mesenchymal transition and stem-cell pluripotency. KLF4 is one of Yamanaka reprogramming factors, and plays context-dependent tumor-suppressive or oncogenic roles across tissues. It sustains epithelial homeostasis in skin and intestine; dysregulated KLF4 occurs in multiple cancers.