Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Lamin B1 Rabbit mAb [29E96]
抗Lamin B1兔单克隆抗体 [29E96]
Cat. No.
A52202
Clone No. 29E96
SynonymsLamin B1, Lamin-B1, Lamin B, LBR, LBR protein
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
68 kDa
Observed MW
68 kDa
Clonality
Monoclonal
Clone No.
29E96
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
LMNB1
Protein Name
Lamin B1
Background
Lamin B1 belongs to type-V intermediate filament family and localizes to nuclear lamina beneath inner nuclear membrane. It builds nuclear skeleton to preserve nuclear morphology and envelope integrity, and participates in chromatin anchoring, gene regulation and DNA-damage repair. Lamin B1 serves as a canonical nuclear-integrity marker, and its down-regulation is a hallmark of cellular senescence. Lamin B1 defects cause laminopathies.
Localization
Nucleus
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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