Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-LC3A Rabbit mAb [38G33]
抗LC3A兔单克隆抗体 [38G33]
Cat. No.
A52204
Clone No. 38G33
SynonymsLC3-A, LC3A, MAP1LC3A
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
14 kDa
Observed MW
16 kDa
Clonality
Monoclonal
Clone No.
38G33
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
MAP1LC3A
Protein Name
Microtubule-associated protein-1 light chain-3 alpha
Background
LC3A (Microtubule-associated protein light chain 3A) belongs to LC3/GABARAP autophagy-protein family. Cytosolic soluble LC3A-I undergoes lipidation to produce LC3A-II, which stably inserts into autophagosomal membranes. LC3A drives autophagosome biogenesis and elongation and represents a bona-fide autophagosome marker. Autophagy induction leads to LC3A-II accumulation, while functional autophagic flux mediates LC3A-II turnover in lysosomes.
Localization
Autophagosome Membrane
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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